Interaction between isoprenaline and aminophylline in asthma

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Interaction between isoprenaline and aminophylline in asthma.

Campbell, I. A., Middleton, W. G., McHardy, G. J. R., Shotter, Margaret V., McKenzie, R., and Kay, A. B. (1977). Thorax, 32, 424-428. Interaction between isoprenaline and aminophylline in asthma. Using a factorially designed study, 38 patients with bronchial asthma received a single dose of either isoprenaline by inhalation (9), aminophylline intravenously (10), isoprenaline and aminophylline (...

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Response of blood gas tensions to aminophylline and isoprenaline in patients with asthma.

Aminophylline and isoprenaline, two drugs widely used in the managem2nt of asthma, have a pulmonary vasodilator action as well as a bronchodilator action. If regional pulmonary vasoconstriction in poorly ventilated parts of the lungs is a significant compensatory phenomenon in asthma, the effects of administration of these agents on gas exchange would depend on the relative magnitudes of bronch...

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Possible interaction between aminophylline and ascorbic acid.

Acocella, G. (1978). Clinical pharmacokinetics of rifampicin. Clin. Pharmacokin., 3, 108-127. Binda, G., Domenichini, E., Gottardi, A., Orlandi, B., Ortelli, E., Pacini, B. & Fowst, G. (1971). Rifampicin, a general review. Arzneim-Forsch., 21, 1907-1977. Conney, A. H. (1967). Pharmacological implications of microsomal induction. Pharmac. Rev., 19, 317366. Das, K. M. & Dubin, R. (1976). Clinical...

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Asthma guidelines: why aminophylline?

274 May 2013, Vol. 103, No. 5 SAMJ Asthma guidelines: Why aminophylline? To the Editor: While it is always encouarging to see new clinical guidelines to help direct therapy for important clinical conditions, the ‘Guidelines for the management of acute asthma in adults’ are disappointing in two regards. Firstly, a majority of acute asthma attacks in adults are managed in the emergency centre and...

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Intravenous salbutamol and aminophylline in asthma: a search for synergy.

The bronchodilation produced by increasing intravenous doses of aminophylline, salbutamol, and a combination of aminophylline and salbutamol given in random order was determined in 10 stable asthmatics on three consecutive days. On a fourth day, response to placebo injections was determined. Forced expiratory volume in one second (FEV1) was measured at two-minute intervals after each dose until...

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ژورنال

عنوان ژورنال: Thorax

سال: 1977

ISSN: 0040-6376

DOI: 10.1136/thx.32.4.424